N-Benzoyl-(2R,3S)-3-phenylisoserine-product

Description	N-Benzoyl-(2R,3S)-3-phenylisoserine (taxol side chain) is an intermediate in the preparation of potent anticancer drug Paclitaxel, used to study the location of the binding sites. It shows cytotoxic, antiviral and immunomodulatory activity.
Synonyms	N-苯甲酰基-(2R,3S)-3-苯基异丝氨酸, taxol side chain
molecular weight	285.29
Molecular formula	C16H15NO4
CAS	132201-33-3
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility	DMSO: 52 mg/mL(182.3 mM) Ethanol: Soluble
References	1. Paal K, et al. Paclitaxel binding to human serum albumin--automated docking studies[J]. Bioorganic & Medicinal Chemistry, 2007, 15(3):1323-1329. 2. Krawczyk E, et al. Cytotoxic, antiviral (in‐vitro and in‐vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10‐deacetyl‐baccatin III, methyl (N‐benzoyl‐(2‘R,3’S)‐3‘‐phenylisoserinate) and N‐benzoyl‐(2’R[J]. Journal of Pharmacy & Pharmacology, 2010, 57(6):791-797.

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