| Description | N-acetyl-D-Lactosamine (N-Acetyllactosamine) is a disaccharide consisting of galactose and N-acetylglucose, which is an important component of various oligosaccharides and can be used as a starting material for the synthesis of various oligosaccharides. N-acetyl-D-Lactosamine may be used as a structural element naturally in various sugar conjugates and can also be used to characterise lectins, which have probiotic effect. |
| In vitro | N-acetyl-D-Lactosamine（10 microg/ml）对人类外周血单核细胞具有强大的促进分裂作用。[3] 而N-acetyl-D-Lactosamine（100 microg/ml）对SiHa（人类宫颈）癌细胞系显示出50%的生长抑制效力。[3] |
| Synonyms | N-Acetyllactosamine |
| molecular weight | 383.35 |
| Molecular formula | C14H25NO11 |
| CAS | 32181-59-2 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMF: 0.5 mg/mL PBS (pH 7.2): 10 mg/mL H2O: 90.0 mg/mL (234.8 mM ), Sonication is recommended. Ethanol: Slightly soluble DMSO: 30 mg/mL |
| References | 1. Endo T, et al. Large-scale production of N-acetyllactosamine through bacterial coupling. Carbohydr Res. 1999 ; 316(1-4):179-183. 2. Alavijeh M K, et al. Simulation and economic assessment of large-scale enzymatic N-acetyllactosamine manufacture. Biochemical Engineering Journal. 2020 ; 154: 107459. 3. Kaur A, et al. Isolation of a novel N-acetyl-D-lactosamine specific lectin from Alocasia cucullata (Schott.). Biotechnol Lett. 2005 ; 27(22):1815-1820. 4. Rojas-Osnaya J, et al. Novel transglycosylation activity of β-N-acetylglucosaminidase of Lecanicillium lecanii produced by submerged culture. Int J Biol Macromol. 2020 ; 145:759-767. |