| Description | Myrcene is a terpene that has been found in Cannabis and has antioxidative properties. |
| In vivo | Myrcene在大鼠体内表现出抗氧化活性，并以时间依赖的方式消除了TCDD引起的氧化应激。 |
| Animal experiments | Rats (n = 112) were divided randomly into 8 equal groups. One group was kept as control and given corn oil as carrier. TCDD was orally administered at the dose of 2 μg/kg/week. Curcumin, myrcene and cineole were orally administered at the doses of 100 mg/kg/day, 200 mg/kg/day and 100 mg/kg/ day, respectively, by gavages dissolved in corn oil with and without TCDD. The liver samples were taken from half of all rats on day 30 and from the remaining half on day 60 for the determination of thiobarbituric acid reactive substances (TBARS), reduced glutathione (GSH), catalase (CAT), glutathione peroxidase (GSH-Px) and CuZn-SOD levels by spectrophotometric method. The results indicated that although TCDD significantly (p ≤ 0.01) increased formation of TBARS, it caused a significant decline in the levels of GSH, CAT, GSH-Px and CuZn-SOD in rats. |
| molecular weight | 136.23 |
| Molecular formula | C10H16 |
| CAS | 123-35-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (403.71 mM) |
| References | 1. Ciftci O, Ozdemir I, Tanyildizi S, et al. Antioxidative effects of curcumin, β-myrcene and 1,8-cineole against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced oxidative stress in rats liver[J]. Toxicol Ind Health. 2011 Jun;27(5):447-53 |