| Description | Murrayone, a coumarin-containing compound derived from M. paniculata, stands out as the most bioactive substance within this species, primarily due to its unique pharmacological attributes that notably suppress cancer metastasis, positioning it as an effective chemopreventive agent. |
| In vitro | Structures of the isolates were determined by spectroscopic analysis as 10 coumarins: bergapten (1), xanthotoxin (2), isopimpinellin (3), isogosferal (4), imperatorin (5), meransin hydrate(6), isomeranzin(7), Murrayone(8) , auraptenol(9), and osthol(10). In addition to compound 9, the others were isolated from the genus Leonurus for the first time. |
| molecular weight | 258.27 |
| Molecular formula | C15H14O4 |
| CAS | 19668-69-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4.4 mg/mL (17.04 mM) |
| References | 1. Coumarins from Leonurus japonicus and their anti-platelet aggregative activityZhongguo Zhong Yao Za Zhi. 2014 Nov;39(22):4356-9. |