| Description | Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties. |
| In vitro | Moringin通过β-catenin-PPARγ轴调节神经炎症，并通过抑制GSK3β激活Wnt典型途径，在实验性自体免疫性脑炎的小鼠模型中发挥作用。Moringin通过激活p53和Bax、抑制Bcl-2有效诱导凋亡。Moringin在人类恶性星形细胞瘤细胞中展现出抗肿瘤效应。Cannabidiol（5μM）与Moringin（5μM）的组合具有抗炎、抗氧化和抗凋亡效果[1]。 |
| molecular weight | 311.35 |
| Molecular formula | C14H17NO5S |
| CAS | 73255-40-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 62.5 mg/mL (200.74 mM ), Sonication is recommended. |
| References | 1. Rajan TS, et al. Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages. Fitoterapia. 2016 Jul;112:104-15. 2. Rajan TS, et al. Anticancer activity of glucomoringin isothiocyanate in human malignant astrocytoma cells. Fitoterapia. 2016 Apr;110:1-7. |