| Description | Mogroside IIA1 (Mogroside II-A1) is isolated from the fruits of Siraitia grosvenorii. Mogroside IIA1 is a a nonsugar sweetener and sweeter than sucrose. Mogroside IIA1 possesses antioxidant, antidiabetic and anticancer activities. |
| In vitro | Mogroside IIA1显示出抑制效果，其IC50值为346-400摩尔比/32 pmol TPA。莫格罗苷II-A1对激活(+/-)-(E)-甲基-2-[(E)-羟亚胺基]-5-硝基-6-甲氧基-3-己内酰胺（NOR 1），一种一氧化氮（NO）供体[1]，表现出弱抑制效果。 |
| Synonyms | Mogroside II-A1, 罗汉果苷II A1 |
| molecular weight | 801.01 |
| Molecular formula | C42H72O14 |
| CAS | 88901-44-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 95 mg/mL (118.60 mM), Sonication is recommended. |
| References | 1. Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein-Barr virus activation.J Nat Prod. 2007 May;70(5):783-8. 2. Itkin M, et al. The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii.Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7619-E7628. |