| Description | methyl isoeugenol (MIE) is a natural food flavour that constitutes 93.7% of an essential oil from Pimenta pseudocaryophyllus leaf. The leaf extracts of this species are used as a calming agent. As a ubiquitous food additive, the application of MIE for treating mood disorders. |
| In vivo | Anti-immobility effect of Methyl isoeugenol?250 mg kg(-1) in the FST suggested an antidepressive like property.?Unlike AMPT, pretreatment with PCPA reversed the antidepressant like effect ofMethyl isoeugenol.?Anxiolytic and antidepressant like properties of Methyl isoeugenol?and suggested the participation?of serotonergic pathways[1]. |
| molecular weight | 178.23 |
| Molecular formula | C11H14O2 |
| CAS | 93-16-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (336.64 mM) |
| References | 1. Fajemiroye J O , Galdino P M , De Paula J A M , et al. Anxiolytic and antidepressant like effects of natural food flavour (E)-methyl isoeugenol[J]. Food & Function, 2014, 5(8):1819. 2. Fajemiroye J O , Da Silva E F , De Oliveira T S , et al. Hypotensive and vasorelaxant effects of (E) – Methyl isoeugenol: A naturally occurring food flavour[J]. Food and Chemical Toxicology, 2014, 70:214-221. |