| Description | Menthol (DL-Menthol) is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties. |
| In vivo | High levels of the major DL-Menthol metabolite, menthol-glucuronide, was observed in the urine of smokers of either menthol or non-menthol cigarettes. The fact that a significant inverse correlation was observed between the levels of urinary menthol-glucuronide and NNAL-N-glucuronide, a major detoxification metabolite of the tobacco carcinogen, NNK, suggests that menthol may be inhibiting the clearance of this important tobacco carcinogen. |
| Synonyms | 薄荷脑, DL-Menthol |
| molecular weight | 156.26 |
| Molecular formula | C10H20O |
| CAS | 1490-04-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (319.98 mM) |
| References | 1. Kozlovich S, Chen G, Watson CJ,et al.The role of L- and D-menthol in the glucuronidation and detoxification of the major lung carcinogen, NNAL[J].Drug Metab Dispos. 2019 Oct 2. pii: dmd.119.088351 |