| Description | Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. |
| Synonyms | Carboxyacetic Acid, 1,3-Propanedioic Acid, 丙二酸, Propanedioic Acid |
| molecular weight | 104.06 |
| Molecular formula | C3H4O4 |
| CAS | 141-82-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (528.54 mM) |
| References | 1. Ohdoi C, et al. Chemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jul 15;792(1):123-30. |