| Description | Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects. |
| Target activity | ERK2:16.5 nM, ERK1:87 nM |
| Synonyms | 木兰脂素, (+)-Magnolin, 木兰苷 |
| molecular weight | 416.46 |
| Molecular formula | C23H28O7 |
| CAS | 31008-18-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 75 mg/mL(180.1 mM) Chloroform, Dichloromethane, Ethyl Acetate: Soluble |
| References | 1. Wang F,et al. Magnolin protects against contrast-induced nephropathy in rats via antioxidation and antiapoptosis. Oxid Med Cell Longev. 2014;22014:203458. 2. Lee CJ,et al. Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation. Carcinogenesis. 2014 Feb;35(2):432-41. |