| Description | (+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mechanism other than prevention of micelle formation or protection of the erythrocyte membrane against osmotic imbalance. |
| Synonyms | Escholin, Magnoflorine, Thalictrin, Escholine, 木兰花碱 |
| molecular weight | 342.41 |
| Molecular formula | C20H24NO4 |
| CAS | 2141-09-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 34.24 mg/mL (100 mM), Sonication is recommended. Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. PenA J B I D L , Lee H L , Seo Young Yoon, et al. The involvement of magnoflorine in the sedative and anxiolytic effects ofSinomeni Caulis et Rhizomain mice[J]. Journal of Natural Medicines, 2013, 67(4):814-821. |