| Description | Lobelanidine (8,10-Diphenyllobelidiol), which can be extracted from the above-ground parts of Lobelia chinensis Lour and Lobelia tupa, is an analogue of lobeline and shows a moderate affinity for nAChR. |
| Synonyms | NSC-95097, 8,10-Diphenyllobelidiol, NSC 95097, NSC95097 |
| molecular weight | 339.47 |
| Molecular formula | C22H29NO2 |
| CAS | 552-72-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4.8 mg/mL (14.14 mM) |
| References | 1. Paz C, et al. (-)-Pentylsedinine, a New Alkaloid from the Leaves of Lobelia tupa with Agonist Activity at Nicotinic Acetylcholine Receptor. Nat Prod Commun. 2015;10(8):1355-1357. 2. Chênevert R, et al. Synthesis of (-)-lobeline via enzymatic desymmetrization of lobelanidine. Bioorg Med Chem. 2009;17(5):1837-1839. 3. Chen MW, et al. Lobelia chinensis: chemical constituents and anticancer activity perspective. Chin J Nat Med. 2014;12(2):103-107. 4. Birman VB, et al. Enantioselective synthesis of lobeline via nonenzymatic desymmetrization. Org Lett. 2007;9(17):3237-3240. |