| Description | Littorine is a tropane alkaloid found in a variety of plants including Datura and Atropa belladonna. It is closely related in chemical structure to atropine, hyoscyamine, and scopolamine, which all share a common biosynthetic pathway. |
| Synonyms | (R)-(-)-Littorine |
| molecular weight | 289.375 |
| Molecular formula | C17H23NO3 |
| CAS | 21956-47-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Li R, Reed DW, Liu E, Nowak J, Pelcher LE, Page JE, Covello PS. Functional genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement. Chem Biol. 2006 May;13(5):513-20. PubMed PMID: 16720272. 2. Nasomjai P, Reed DW, Tozer DJ, Peach MJ, Slawin AM, Covello PS, O'Hagan D. Mechanistic insights into the cytochrome P450-mediated oxidation and rearrangement of littorine in tropane alkaloid biosynthesis. Chembiochem. 2009 Sep 21;10(14):2382-93. doi: 10.1002/cbic.200900318. PubMed PMID: 19693762. 3. Al Balkhi MH, Schiltz S, Lesur D, Lanoue A, Wadouachi A, Boitel-Conti M. Norlittorine and norhyoscyamine identified as products of littorine and hyoscyamine metabolism by (13)C-labeling in Datura innoxia hairy roots. Phytochemistry. 2012 Feb;74:105-14. doi: 10.1016/j.phytochem.2011.10.010. Epub 2011 Nov 13. PubMed PMID: 22083085. 4. Mateus L, Cherkaoui S, Christen P, Oksman-Caldentey KM. Simultaneous determination of scopolamine, hyoscyamine and littorine in plants and different hairy root clones of Hyoscyamus muticus by micellar electrokinetic chromatography. Phytochemistry. 2000 Jun;54(5):517-23. PubMed PMID: 10939356. |