| Description | Lirinidine is an alkaloid isolated from L. tulipifera leaves with antioxidant and anticancer properties. It exhibits moderate iron-reducing capacity and small free radical scavenging capacity in vitro and can be used in cosmetic research. |
| In vitro | 从Liriodendron tulipifera叶中提取并纯化了十六种化合物，这些化合物包括aporphines、oxoaporphine、coumarin、sesquiterpene lactone、benzenoids、cyclitol和steroids。首次从Liriodendron tulipifera叶中分离出(+)-Norstephalagine (2)（一种aporphine）和scopoletin (8)（一种coumarin）。所鉴定化合物的抗自由基清除、金属螯合和铁还原能力活性得到了筛查，结果显示这些化合物具有抗氧化活性。此研究还探讨了这些化合物对人类黑色素瘤细胞A375的化预防性质，结果表明(-)-anonaine (1)、(-)-liridinine (3)、(+)-Lirinidine (6)、lysicamine (7)和epitulipinolide diepoxide (9)显著抑制了黑色素瘤细胞的增殖[1]。 |
| molecular weight | 281.35 |
| Molecular formula | C18H19NO2 |
| CAS | 54383-28-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/ml (195.49 mM) |
| References | 1. Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera.Molecules. 2014 Apr 3;19(4):4234-45. |