| Description | Lignoceric Acid (tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid and a by-product of lignin production, which is synthesized in the developing brain. |
| In vitro | 通过等温滴定量热法评估了肝癌细胞(HepG2)及X-ALD患者和健康受试者来源的成纤维细胞中分离的过氧化物酶体内由Lignoceric Acid引发的产热通量。Lignoceric Acid在HepG2细胞过氧化物酶体中引发的热通量为放热反应，表明了正常的过氧化物酶体代谢作用[2]。 |
| Synonyms | 二十四烷酸, tetracosanoic acid |
| molecular weight | 368.64 |
| Molecular formula | C24H48O2 |
| CAS | 557-59-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: < 1 mg/mL (insoluble or slightly soluble) Ethanol: 1 mg/mL (2.7 mM), Sonication and heating to 50℃ are recommended. |
| References | 1. Chung HK, et al. Plasma phospholipid arachidonic acid and lignoceric acid are associated with the risk of cardioembolic stroke. Nutr Res. 2015 Nov;35(11):1001-8. 2. Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234(10):18344-18348. |