| Description | Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease. |
| In vivo | Repeated administration of lansoprazole to humans induces the hepatic microsomal P-450-dependent drug oxidation system that mediates N-1-demethylation of theophylline, consequently increasing its metabolism[1]. |
| Synonyms | 兰索拉唑钠, Lansoprazole (sodium), AG-1749 sodium |
| molecular weight | 391.34 |
| Molecular formula | C16H13F3N3NaO2S |
| CAS | 226904-00-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (153.32 mM) |
| References | 1. Kokufu T , Ihara N , Sugioka N , et al. Effects of lansoprazole on pharmacokinetics and metabolism of theophylline[J]. European Journal of Clinical Pharmacology, 1995, 48(5):391-5. |