| Description | L-(+)-Arabinose inhibits intestinal sucrase activity, thereby reducing sucrose utilization, and consequently decreasing lipogenesis. |
| In vitro | L-(+)-Arabinose 与核糖-5-磷酸异构酶缺乏症有关，这是一种先天性代谢障碍[1]。L-(+)-Arabinose 选择性地以非竞争性方式抑制肠道蔗糖酶活性，从而抑制由于蔗糖摄入引起的血浆葡萄糖增加[1]。 |
| In vivo | L-(+)-Arabinose喂食显著降低了大鼠的附睾脂肪组织重量。同时，血浆胰岛素和三酰甘油水平也因饮食中加入L-(+)-Arabinose而显著下降[1]。L-(+)-Arabinose通过调节AMP激活蛋白激酶抑制代谢紊乱小鼠中的糖异生作用[2]。 |
| molecular weight | 150.13 |
| Molecular formula | C5H10O5 |
| CAS | 5328-37-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (399.65 mM), Sonication is recommended. H2O: 400 mg/mL (2664.36 mM), Sonication is recommended. |
| References | 1. Osaki S, et al. L-arabinose feeding prevents increases due to dietary sucrose in lipogenic enzymes and triacylglycerol levels in rats. J Nutr. 2001 Mar;131(3):796-9. 2. Wang Y, et al. L-Arabinose suppresses gluconeogenesis through modulating AMP-activated protein kinase in metabolic disorder mice. Food Funct. 2021 Mar 1;12(4):1745-1756. |