| Description | Kuwanon E, a flavonoid obtained from Morus alba, has potential anti-inflammatory activity, inhibits TNF-α and IL-1β secretion, and suppresses NF-κB nuclear translocation in LPS-stimulated macrophages. |
| In vitro | 方法：将THP-1细胞暴露24小时，分别达到Kuwanon E的浓度（1,2.5,5,10,20和50 μM），进行染色观察活性，并用血细胞计数器计数。结果：Kuwanon E的LD50值大于50 μM并抑制 THP-1 细胞的增殖。[1] |
| molecular weight | 424.49 |
| Molecular formula | C25H28O6 |
| CAS | 68401-05-8 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: DMSO: 30 mg/mL (70.67 mM), Sonication is recommended. |
| References | 1. Kollar P, et al. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response. Evid Based Complement Alternat Med. 2013;2013:350519. |