| Description | Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K shows weak antiviral activity against Herpes simplex virus types I and II. |
| In vitro | A new prenylated flavonol, sophoflavescenol (1), together with five known flavonoids, kurarinol, Kushenol K, kushenol H, trifolirhizin, and kuraidin, were isolated from the roots of Sophora flavescens. The structure of 1 was determined by spectroscopic analysis[1] |
| Target activity | CYP3A4:1.35 μM (Ki), HSV2:147 μM (EC50) |
| molecular weight | 472.53 |
| Molecular formula | C26H32O8 |
| CAS | 101236-49-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. A new prenylated flavonol from the roots of Sophora flavescens.J Nat Prod. 1998 Dec;61(12):1552-4. |