Kaempferol 3,7,4'-trimethyl ether-product

Description	Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) shows selective cyctoxic activities against the nine tested cancer cell lines.
In vitro	The IC50 values below or around 30 μg/mL were recorded with A. arundinaceum extract against eight of the nine tested cancer cell lines. This extract displayed IC50 values below 40 μg/mL towards the nine tested cancer cell lines whilst A. polyanthum extract, Kaempferol 3,7,4'-trimethylether showed selective activities. Collateral sensitivity (hypersensitivity) was observed with A. arundinaceum extract towards leukemia CEM/ADR5000 cells and glioblastoma U87MG.ΔEGFR compared to their respective sensitive counterparts CEM/CEM and U87MG.[1]
Synonyms	莰非醇-3,7,4'-三甲醚, 莰非醇三甲醚, Kaempferol 3,7,4'-trimethylether
molecular weight	328.32
Molecular formula	C18H16O6
CAS	15486-34-7
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility	DMSO: 11 mg/ml (33.5 mM)
References	1. Kuete V, Ango PY, et al. Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines. BMC Complement Altern Med. 2014 Sep 19;14:340.

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