| Description | Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells. Isoliquiritin apioside has marked potential to combat oxidative stress-induced genotoxicity. |
| molecular weight | 550.51 |
| Molecular formula | C26H30O13 |
| CAS | 120926-46-7 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 5.5 mg/mL (10 mM), Sonication is recommended. |
| References | 1. Kim A1, et al. Isoliquiritin Apioside Suppresses in vitro Invasiveness and Angiogenesis of Cancer Cells and Endothelial Cells.Front Pharmacol. 2018 Dec 10;9:1455. 2. Kaur P , Kaur S , Kumar N , et al. Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L.[J]. toxicology in vitro, 2009, 23(4):0-686. |