| Description | Icariside I (Lcariside I) is isolated from Epimedium herb. It can stimulate osteogenic differentiation of BMSCs and inhibit bone resorption activity of osteoclasts. |
| Synonyms | 淫羊藿次苷I, Lcariside I, Icariin I, Icarisid I |
| molecular weight | 530.52 |
| Molecular formula | C27H30O11 |
| CAS | 56725-99-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 75 mg/mL (141.37 mM), Sonication is recommended. |
| References | 1. Ming LG,et al. Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling. J Cell Physiol. 2013 Mar;228(3):513-21 2. Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2020 3. Gao Y, Xu G, Ma L, et al. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2021, 19(1): 1-14. |