| Description | Hypotaurine (2-Aminoethanesulfinic acid), functioning as an intermediate in the biosynthesis of taurine from cysteine within astrocytes, acts as an endogenous inhibitory amino acid targeting the glycine receptor. |
| Synonyms | 2-Aminoethanesulfinic acid, 亚牛磺酸, 2-Aminoethylsulfinic acid |
| molecular weight | 109.15 |
| Molecular formula | C2H7NO2S |
| CAS | 300-84-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 150 mg/mL (1374.26 mM) |
| References | 1. Green TR, et al. Antioxidant role and subcellular location of hypotaurine and taurine in human neutrophils. Biochim Biophys Acta. 1991 Jan 23;1073(1):91-7. 2. Gao P, et al. Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling. Oncotarget. 2016 Mar 22;7(12):15200-14. |