| Description | Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor. |
| In vitro | Hydroxyzine是具有镇静特性的抗组胺药，用于控制焦虑和呕吐。 |
| Synonyms | Hydroxyzine free base, 羟嗪 |
| molecular weight | 374.9 |
| Molecular formula | C21H27ClN2O2 |
| CAS | 68-88-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 14 mg/mL (37.34 mM) |
| References | 1. Mcintyre I M , Mallett P , Trochta A , et al. Hydroxyzine distribution in postmortem cases and potential for redistribution[J]. Forensic ence International, 2013, 231(1-3):28-33. 2. Knych H K , Weiner D , Steinmetz S , et al. Pharmacokinetics of hydroxyzine and cetirizine following oral administration of hydroxyzine to exercised Thoroughbred horses[J]. Journal of Veterinary Pharmacology and Therapeutics, 2019, 42(8). |