| Description | Humantenirine is a natural product of Gelsemium, Loganiaceae. The catalog number is TN1748 and the CAS number is 82375-30-2. Humantenirine can be used as a reference standard. |
| In vitro | A new pregnane derivative, 12 beta-hydroxy-5 alpha-pregn-16-ene-3,20-dione, along with the known derivative 12 beta-hydroxy-pregna-4,16-diene-3,20-dione have been isolated from a MeOH extract of the stem of Gelsemium sempervirens and found to be the principal cytotoxic entities. The 13C-nmr spectra of both compounds were assigned by comparison with other pregnane analogs thereby allowing confirmation of the stereochemistry at C-5 in compound. Heteronuclear 2D correlation and selective INEPT experiments indicated the need to revise a number of 13C-nmr assignments of pregn-4,16-dien-3,20-dione. |
| molecular weight | 370.44 |
| Molecular formula | C21H26N2O4 |
| CAS | 82375-30-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Cytotoxic steroids of Gelsemium sempervirens.J Nat Prod. 1987 Mar-Apr;50(2):195-8. |