| Description | HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species. |
| molecular weight | 259.34 |
| Molecular formula | C16H21NO2 |
| CAS | 341-88-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 2.59 mg/mL (10 mM), Sonication is recommended. |
| References | 1. Jessica Petri, et al. Structure of the NDH-2 - HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):482-490. 2. Kang J , Kim Y J . HQNO-sensitive NADH:Quinone Oxidoreductase of Bacillus cereus KCTC 3674[J]. J Biochem Mol Biol, 2007, 40(1):53-57. |