Description | Glochidiol exhibits strong inhibitory effects against all three human tumor cell lines (MCF-7, NCI-H-460 and SF-268), it exerts its antiproliferative activity through the involvement of apoptosis. It exhibits a strong inhibitory effect on mouse skin tumor promotion in an in vivo mouse two-stage carcinogenesis test. Glochidiol (IC50 = 290 mol ratio/32 pmol TPA) also shows inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol 13-acetate (TPA). |
molecular weight | 442.72 |
Molecular formula | C30H50O2 |
CAS | 6610-56-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |