| Description | Ganodermanontriol, a sterol derived from Ganoderma lucidum, showcases hepatoprotective activity and possesses anti-inflammatory properties in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the upregulation of HO-1 expression. |
| In vitro | Ganodermanontriol inhibits breast cancer cell lines MDA-MB-231 and MCF-7?with IC50 values of 9.7 and 5.8 μM, respectively. |
| molecular weight | 472.7 |
| Molecular formula | C30H48O4 |
| CAS | 106518-63-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Ha do T, et al. In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress. Ethnopharmacol. 2013 Dec 12;150(3):875-85. 2. Kennedy EM, et al. Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols. J Nat Prod. 2011 Nov 28;74(11):2332-7. |