| Description | Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 microM (+)-eudesmin can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways. |
| molecular weight | 386.44 |
| Molecular formula | C22H26O6 |
| CAS | 526-06-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25 mg/mL (64.69 mM) |
| References | 1. Cho J Y , Yoo E S , Baik K U , et al. Eudesmin inhibits tumor necrosis factor-alpha production and T cell proliferation[J]. Archives of Pharmacal Research, 1999, 22(4):348-353. |