| Description | ent-17-Hydroxykaur-15-en-19-oic acid is a natural compound found in the leaves of the aromatic tree and has an IC50 of 17.63microg/mL on human prostate cells. |
| In vitro | Ent-17-Hydroxykaur-15-en-19-oic acid (6-50microg/mL) 对人类前列腺(22Rv1, LNCaP)、结肠(HT29, HCT116, SW480, SW620)及乳腺(MCF-7)肿瘤细胞进行了细胞性毒性评估。结果显示,在所有测试的细胞系中均表现出活性,其中前列腺细胞最为敏感(IC(50) 17.63microg/mL)。[1] |
| Target activity | Prostate cells:17.63microg/mL |
| molecular weight | 318.45 |
| Molecular formula | C20H30O3 |
| CAS | 35030-38-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Henry GE, et al. Kaurene diterpenes from Laetia thamnia inhibit the growth of human cancer cells in vitro. Cancer Lett. 2006 ; 244(2):190.194. 2. Matsumoto S, et al. Bio-guided optimization of the ultrasound-assisted extraction of compounds from Annona glabra L. leaves using the etiolated wheat coleoptile bioassay. Ultrason Sonochem. 2014 ; 21(4):1578-1584. |