| Description | 1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney. 2. Desoxyrhaponticin and rhaponticin could be considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
| Synonyms | 去氧土大黄苷, Deoxyrhapontin, 脱氧土大黄苷, Deoxyrhaponticin |
| molecular weight | 404.41 |
| Molecular formula | C21H24O8 |
| CAS | 30197-14-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (123.64 mM) |
| References | 1. Li P , Tian W , Wang X , et al. Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan medicinal plant Rheum tanguticum Maxim. ex Balf, on fatty acid synthase and human breast cancer cells[J]. Food & Function, 2014, 5(2):251-256. |