| Description | Deoxypyridinoline is one of two pyridinium cross-links that provide structural stiffness to type I collagen found in bones. It is excreted unmetabolized in urine and is a specific marker of bone resorption and osteoclastic activity. |
| Synonyms | Lysylpyridinoline |
| molecular weight | 412.443 |
| Molecular formula | C18H28N4O7 |
| CAS | 90032-33-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Tabatabaei N, Rodd CJ, Kremer R, Weiler HA. Osteocalcin, but not deoxypyridinoline, increases in response to isoflurane-induced anaesthesia in young female guinea pigs. J Bone Miner Metab. 2015 May;33(3):253-60. doi: 10.1007/s00774-014-0593-7. Epub 2014 May 24. PubMed PMID: 24858976. 2. Shi J, Wang Z, Li H, Yuan H. Diagnostic performance of the urinary deoxypyridinoline in spinal tuberculosis. Orthopedics. 2012 Jun;35(6):e922-6. doi: 10.3928/01477447-20120525-36. PubMed PMID: 22691668. 3. Ochoa-Martínez PY, Hall-Lopez JA, Ávila FA, Rocha CA, Moreira MH, Dantas EH. Effect of three months of periodized hydrogymnastics exercise program on urinary concentration of deoxypyridinoline in older women. Arch Endocrinol Metab. 2015 Dec;59(6):523-7. doi: 10.1590/2359-3997000000102. PubMed PMID: 26677086. 4. Vanderspank D, Bernier SM, Sopper MM, Watson P, Mottola MF. Activity restriction increases deoxypyridinoline excretion in hospitalized high-risk pregnant women. Biol Res Nurs. 2014 Jan;16(1):7-15. doi: 10.1177/1099800412463120. Epub 2012 Oct 17. PubMed PMID: 23079370. |