| Description | Deoxyartemisinin (2-deoxyartemisinin), a compound derived from Artemisia annua, has anti-inflammatory and anti-ulcer effects and is used in the study of malaria. |
| In vitro | Biotransformation of artemisinin was investigated with two different cell lines of suspension cultures of Withania somnifera. Both cell lines exhibited potential to transform artemisinin into its nonperoxidic analogue, Deoxyartemisinin, by eliminating the peroxo bridge of artemisinin. The enzyme involved in the reaction is assumed to be artemisinin peroxidase, and its activity in extracts of W. somnifera leaves was detected[1] |
| Synonyms | 2-deoxyartemisinin |
| molecular weight | 266.33 |
| Molecular formula | C15H22O4 |
| CAS | 72826-63-2 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Chunqing Fu, et al. Oral Bioavailability Comparison of Artemisinin, Deoxyartemisinin, and 10-Deoxoartemisinin Based on Computer Simulations and Pharmacokinetics in Rats. ACS Omega. 2020 Dec 28;6(1):889-899. |