Description | Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and extrinsic pathway, followed by downstream events leading to apoptotic cell death, it could therefore, serve as a useful agent to treat human advanced prostate cancer. |
molecular weight | 349.434 |
Molecular formula | C21H23N3O2 |
CAS | 111768-16-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |