Description | Delta-Tocopherol is an isomer of Vitamin E,has antioxidant activity,and might be useful as effective ingredients in whitening cosmetics with lower skin toxicity. |
In vitro | D-beta-tocopherol at 250 mug ml(-1) inhibited not only 28% of melanin synthesis in B16 cells, but also 34% of the tyrosinase activity, a very important cascade enzyme involved in the synthesis of melanin in melanoma cells. D-gamma-tocopherol also strongly inhibited up to 39% of melanin synthesis and 45% of the tyrosinase enzyme activity at the same concentration. |
Synonyms | (+)-DELTA-生育酚, D-DELTA-TOCOPHEROL |
molecular weight | 402.65 |
Molecular formula | C27H46O2 |
CAS | 119-13-1 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 125 mg/mL (310.44 mM) |
References | 1. Kamei Y , Otsuka Y , Abe K . Comparison of the inhibitory effects of vitamin E analogues on melanogenesis in mouse B16 melanoma cells[J]. Cytotechnology, 2009, 59(3):183-190. |