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δ-Amyrenone

CAS No.: 20248-08-2

δ-Amyrenone (Delta-Amyrone), isolated from S. lineare, has anti-inflammatory effects.
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Description δ-Amyrenone (Delta-Amyrone), isolated from S. lineare, has anti-inflammatory effects.
In vivo Delta-starch dextrin(4 mg/kg和8 mg/kg;腹腔注射)能够抑制脂多糖诱导的炎症性细胞因子,并保护小鼠免受内毒素休克。
Synonyms Delta-Amyrone, Α-香树脂酮
molecular weight 424.7
Molecular formula C30H48O
CAS 20248-08-2
Storage keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: Slightly soluble
References 1. Niu X, et al.δ-Amyrone, a specific inhibitor of cyclooxygenase-2, exhibits anti-inflammatory effects in vitro and in vivo of mice. Int Immunopharmacol. 2014 Jul;21(1):112-8. 2. Niu X, et al.δ-Amyrone inhibits lipopolysaccharide-induced inflammatory cytokines and protects against endotoxic shock in mice. Chem Biol Interact. 2015 Oct 5;240:354-61.