| Description | 1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially attributed to DHC. 2. Dehydrocorydaline can inhibit elevated mitochondrial membrane potential in lipopolysaccharide-stimulated macrophages. 3. Dehydrocorydaline has antinociceptive effects in mouse models of inflammatory pain, the effects involve the opioid receptor and inflammatory cytokines. 4. Dehydrocorydaline has anti-inflammatory activity. |
| Target activity | P. falciparum (3D7 strain):38 nM (IC50) |
| Synonyms | 去氢延胡索甲素硝酸盐, 硝酸脱氢紫堇碱 |
| molecular weight | 428.44 |
| Molecular formula | C22H24N2O7 |
| CAS | 13005-09-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 27.5 mg/mL (64.19 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. Ishiguro K , Ando T , Maeda O , et al. Dehydrocorydaline inhibits elevated mitochondrial membrane potential in lipopolysaccharide-stimulated macrophages[J]. International Immunopharmacology, 2011, 11(9):0-1367. |