| Description | Daunomycinone (NSC-109351) is a glycan of daunomycin, which belongs to the antibiotic class and is a representative glycan of tumour-inhibiting anthracyclines, used in the treatment of cancer and leukaemia. |
| Synonyms | Daunomycinon, Leukaemomycinone C, NSC 109351, NSC-109351, NSC109351 |
| molecular weight | 398.36 |
| Molecular formula | C21H18O8 |
| CAS | 21794-55-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 3.98 mg/mL (10 mM) |
| References | 1. Arcamone F, et al. The structure of daunomycin. Tetrahedron Lett. 1968 ; (30):3349-3352. 2. Aligiannis N, et al. Synthesis and cytotoxic activity of a new potent daunomycinone derivative. Bioorg Med Chem Lett. 2002 ; 12(24):3505-3507. 3. Aligiannis N, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H. Synthesis and cytotoxic activity of a new potent daunomycinone derivative. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3505-7. PubMed PMID: 12443763. 4. Prikrylová V, Lipavská H, Jizba JV, Fuska J, Podojil M, Vanĕk Z. Synthesis and biological activity of (7S)-O-epoxyalkyl derivatives of daunomycinone. J Antibiot (Tokyo). 1985 Dec;38(12):1714-8. PubMed PMID: 3841537. |