| Description | D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT. |
| molecular weight | 355.43 |
| Molecular formula | C21H25NO4 |
| CAS | 3520-14-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25 mg/mL (70.34 mM) |
| References | 1. Tu M , Sun S , Wang K , et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity[J]. Toxicology, 2013, 311(3):225-230. |