D(+)-Galactosamine hydrochloride-product

Description	D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.
In vivo	In mice, D-galactosamine sensitivity is associated with endotoxin sensitivity and that the former is mediated by lymphoreticular cells, not by hepatocytes[1]
Synonyms	D-半乳糖胺盐酸盐, D-氨基半乳糖盐酸盐, D-Galactosamine HCl
molecular weight	215.63
Molecular formula	C6H14ClNO5
CAS	1772-03-8
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility	DMSO: 50 mg/mL (231.88 mM) PBS: 21.56mg/mL(100mM), Sonification is recommended.
References	1. Chojkier M , Fierer J . D-Galactosamine Ire atotoxicit Is Associated With Endotoxin Sensitivity and Mediated by Lymphoreticular Cells in Mice[J]. Gastroenterology, 1985, 88(1):115-121. 2. Ullrich D , Bock K W . Inhibition of glucuronide formation by D-galactosone or D-galactosamine in isolated hepatocytes[J]. Biochemical Pharmacology, 1984, 33(11):1827-1830. 3. Dhurandhare V M , Wen Y S , Gawande S D , et al. Synthesis of D-Galactosamine and D-Allosamine Derivatives via a Microwave-Assisted Preparation of 1,6-Anhydroglucosamine[J]. Journal of Organic Chemistry, 2016:acs.joc.6b02038.

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