| Description | Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer agent. Cyasterone has antifeeding activity. |
| Synonyms | 杯苋甾酮, Cyasteron |
| molecular weight | 520.65 |
| Molecular formula | C29H44O8 |
| CAS | 17086-76-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 91 mg/mL(174.8 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone: Soluble |
| References | 1. Hirayama Y,et al. Stereochemical assignment of C-24 and C-25 of amarasterone A, a putative biosynthetic intermediate of cyasterone. J Org Chem. 2014 Jun 20;79(12):5471-7. 2. Lu X,et al. Anti-proliferation effects, efficacy of cyasterone in vitro and in vivo and its mechanism. Biomed Pharmacother. 2016 Dec;84:330-339. |