| Description | Cucurbitacin B 2-o-α2-D-glucoside has anticancer activity. |
| In vitro | A process for CuBg biotransformation to CuB was developed for the first time. A strain of Streptomyces species that converts CuBg into CuB was isolated from an enrichment culture of C. melo pedicels. After optimization of conditions for enzyme production and biotransformation, a maximum conversion rate of 92.6 % was obtained at a CuBg concentration of 0.25 g/L. When biotransformation was performed on C. melo pedicel extracts, the CuB concentration in the extracts increased from 1.50 to 3.27 g/L. The conversion rate was almost 100 %. |
| molecular weight | 720.853 |
| Molecular formula | C38H56O13 |
| CAS | 65247-27-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. A biotransformation process for the production of cucurbitacin B from its glycoside using a selected Streptomyces sp.Bioprocess Biosyst Eng. 2016 Sep;39(9):1435-40. |