| Description | 1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastric accommodation. 3. Corydaline exhibits the anti-acetylcholinesterase, antiallergic, and antinociceptive activities. 4. Corydaline has potent inhibition of CYP2C19 and CYP2C9. |
| Target activity | μ opioid receptor:1.23 µM (Ki), Enterovirus 71:25.23 µM (IC50), AChE:226 µM (IC50) |
| Synonyms | Corydalin, 紫堇碱, 延胡索甲素, (+)-Corydaline |
| molecular weight | 369.45 |
| Molecular formula | C22H27NO4 |
| CAS | 518-69-4 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (148.87 mM) |
| References | 1. Ji H Y , Lee H , Kim J H , et al. In vitro metabolism of corydaline in human liver microsomes and hepatocytes using liquid chromatography-ion trap mass spectrometry[J]. Journal of Separation Science, 2012, 35(9):1102-1109. |