| Description | (+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effects, it promotes histamine release, and inhibits the histamine release by substance P, suggests that it may be helpful in regulating mast cell-mediated allergic inflammatory responses. (+)-Columbianetin can be effectively used to protect keratinocytes from UVB induced damage. |
| Synonyms | 二氢山芹醇, (S)-Columbianetin, Columbianetin |
| molecular weight | 246.26 |
| Molecular formula | C14H14O4 |
| CAS | 3804-70-4 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 9 mg/mL (36.55 mM) |
| References | 1. Ahn B N , Kim J A , Kong C S , et al. Protective effect of (2′S)-columbianetin from Corydalis heterocarpa on UVB-induced keratinocyte damage[J]. Journal of Photochemistry & Photobiology B Biology, 2012, 109(none):20-27. 2. Uzi, Afek, and, et al. Columbianetin, a phytoalexin associated with celery resistance to pathogens during storage[J]. Phytochemistry, 1995. |