| Description | Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis. |
| In vitro | C-AR was incubated with the content of the large intestine. The culture solution was collected at different time points and analyzed for the metabolites of C-AR. Eight metabolites were identified by liquid chromatography/quadrupole time-of-flight mass spectrometry. M1, M2 and M5 were the major metabolites. In addition, it was proposed that deglycosylation was the only pathway contributing to the biotransformation of C-AR in rat intestinal microflora. |
| molecular weight | 1807.92 |
| Molecular formula | C82H134O43 |
| CAS | 761425-93-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Identification of the metabolites of anti-inflammatory compound clematichinenoside AR in rat intestinal microflora.Biomed Chromatogr. 2013 Dec;27(12):1767-74. |