| Description | Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia. |
| In vitro | The compounds were isolated and purified by normal and reversed phase column chromatographic methods. Structures were identified by spectroscopic analyses. Their osteoclast inhibition activity was then studied.Thirteen cycloartane triterpenoids were isolated from the rhizomes of C. foetida and were characterized as 25-O-acetyl-cimigenol (1), cimigenol (2), cimicidanol (3), 26-deoxyactein (4), asiaticoside A (5), 23-epi-26-deoxyactein (6), actein (7), 12beta-hydroxycimigenol (8), cimiside E (9), (23R, 24S) 25-O-acetyl-cimigenol-3-O-beta-D-xylopyranoside (10), (23R, 24S) cimigenol-3-O-beta-D-xylopyranoside (11), Cimicifugoside H1 (12) and Cimicifugoside H2 (13). |
| Synonyms | 黑升麻苷H-1 |
| molecular weight | 616.78 |
| Molecular formula | C35H52O9 |
| CAS | 163046-73-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 6.17 mg/mL (10 mM) |
| References | 1. Cycloartane triterpenoid of Cimicifuga foetida.Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1930-4. |