| Description | Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) is a cholesteryl ester. Cholesteryl oleate can be used to synthesize solid lipid nanoparticles which is a nanoparticle-based gene therapy approach. |
| Synonyms | 胆固醇油酸酯, Oleoylcholesterol, Cholesterol Oleate, Cholesteryl cis-9-octadecenoate |
| molecular weight | 651.1 |
| Molecular formula | C45H78O2 |
| CAS | 303-43-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Acetone: 45 mg/mL (69.11 mM), Sonication is recommended. DMSO: 5 mg/mL (7.68 mM), Sonication is recommended. Ethanol: 10 mg/mL (15.36 mM), Sonication and heating to 50℃ are recommended. |
| References | 1. Suñé-Pou M, Prieto-Sánchez S, et al. Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy. Int J Nanomedicine. 2018 May 30;13:3223-3233. 2. Souza SL, et al. Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid. Chem Phys Lipids. 2011 Oct;164(7):664-71. |