| Description | Cefodizime Sodium is a third generation cephalosporin antibiotic, has broad-spectrum activity |
| In vivo | A single dose of cefodizime 1 or 2 g is also useful in treating lower urinary tract infections, particularly uncomplicated infections, with a rate of clinical success of 72 to 88%.?Urogenital gonorrhoea, whether caused by beta-lactamase producing or non-beta-lactamase producing Neisseria gonorrhoeae, is very effectively treated by single dose therapy with intramuscular cefodizime 0.25 to 1 g (virtually 100% cured).?Preliminary data from a small number of patients indicate that cefodizime may also be useful in the treatment of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or treatment of surgical infections[1] |
| molecular weight | 628.6 |
| Molecular formula | C20H18N6Na2O7S4 |
| CAS | 86329-79-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (159.7 mM) |
| References | 1. Henwood J M , Monk J P . Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.[J]. drugs, 1988, 40(3):373-447. 2. Hayashi T , Maruden A , Irimura K , et al. NEPHROTOXICITY OF CEFODIZIME SODIUM IN RATS : Single and 14-day repeated intravenous administration[J]. The Journal of Toxicological Sciences, 1988, 13(SupplementI):285-327. |