| Description | Carpaine, an alkaloid isolated from Carica papaya Linn, has anti-thrombocytopenic activity. It has the anti-plasmodial activity to prevent malaria. |
| In vivo | Carpaine affects the myocardium directly, it reduces cardiac output, stroke work, stroke volume, and cardiac power in rats [3]. |
| molecular weight | 478.71 |
| Molecular formula | C28H50N2O4 |
| CAS | 3463-92-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Zunjar V, et al. Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats. J Ethnopharmacol. 2016 Apr 2;181:20-5. 2. Julianti T, et al. Quantification of the antiplasmodial alkaloid carpaine in papaya (Carica papaya) leaves. Planta Med. 2014 Aug;80(13):1138-42. 3. Hornick CA, et al. Effect of carpaine, a papaya alkaloid, on the circulatory function in the rat. Res Commun Chem Pathol Pharmacol. 1978 Nov;22(2):277-89. |