| Description | Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction. |
| In vitro | The structures of 1-7 were determined on the basis of spectroscopic and chemical methods. Six compounds, 2, 3, 5, and 7-9, and 11 compounds, 1-9, Bryodulcosigenin (10), and bryosigenin (11), respectively, were evaluated for their inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation (1 microg/ear) in mice and on Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA. |
| molecular weight | 474.72 |
| Molecular formula | C30H50O4 |
| CAS | 4965-97-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 65 mg/mL (136.92 mM) |
| References | 1. Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica.J Nat Prod. 2002 Feb;65(2):179-83. |